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Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys

Although inhibition of dopamine transporters (DAT) and the subsequent increase in dopamine clearly play a role in the effects of psychomotor stimulants, the reinforcing effectiveness of DAT inhibitors varies. Previous studies suggest that pharmacokinetic and pharmacodynamic properties of these drugs...

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書誌詳細
主要な著者: Kimmel, Heather L., Negus, S. Stevens, Wilcox, Kristin M., Ewing, Sarah B., Stehouwer, Jeffrey, Goodman, Mark M., Votaw, John R., Mello, Nancy K., Carroll, F. Ivy, Howell, Leonard L.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453312/
https://ncbi.nlm.nih.gov/pubmed/18468667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.03.032
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