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Influence of albumin on itraconazole and ketoconazole antifungal activity: results of a dynamic in vitro study.

The relevance of intense protein binding to the antifungal activity of azole compounds is still a matter of debate. The influence of albumin on the antimicrobial activity of ketoconazole and itraconazole, which exhibit very strong plasma protein binding (99 and 99.8%), was evaluated in vitro. Candid...

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Bibliográfalaš dieđut
Publikašuvnnas:Antimicrob Agents Chemother
Váldodahkkit: Schäfer-Korting, M, Korting, H C, Amann, F, Peuser, R, Lukacs, A
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology (ASM) 1991
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662022/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2053
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