Influence of albumin on itraconazole and ketoconazole antifungal activity: results of a dynamic in vitro study.
The relevance of intense protein binding to the antifungal activity of azole compounds is still a matter of debate. The influence of albumin on the antimicrobial activity of ketoconazole and itraconazole, which exhibit very strong plasma protein binding (99 and 99.8%), was evaluated in vitro. Candid...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662022/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2053 |
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