CCR5Δ32 Genotypes in a German HIV-1 Seroconverter Cohort and Report of HIV-1 Infection in a CCR5Δ32 Homozygous Individual

BACKGROUND: Homozygosity (Δ32/Δ32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease progression. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped a population of 737 HI...

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Autori principali: Oh, Djin-Ye, Jessen, Heiko, Kücherer, Claudia, Neumann, Konrad, Oh, Nari, Poggensee, Gabriele, Bartmeyer, Barbara, Jessen, Arne, Pruss, Axel, Schumann, Ralf R., Hamouda, Osamah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453227/
https://ncbi.nlm.nih.gov/pubmed/18648518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002747
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