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Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in Mycobacterium chelonae.

We calculated the target access index, which reflects the probability that a drug will reach its target at an effective concentration, and the predictive MICs of cephaloridine, cephalothin, and cefazolin for Mycobacterium chelonae from the drug concentrations inhibiting the binding of benzylpenicill...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Jarlier, V, Gutmann, L, Nikaido, H
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1952873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.9.1937
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