Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in Mycobacterium chelonae.

We calculated the target access index, which reflects the probability that a drug will reach its target at an effective concentration, and the predictive MICs of cephaloridine, cephalothin, and cefazolin for Mycobacterium chelonae from the drug concentrations inhibiting the binding of benzylpenicill...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Jarlier, V, Gutmann, L, Nikaido, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1952873/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.9.1937
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