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Development of resistance to fleroxacin during therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditis.

The efficacy of fleroxacin was compared with that of vancomycin by using the rabbit model of methicillin-susceptible Staphylococcus aureus endocarditis. Animals received intravenous therapy with fleroxacin, 30 mg/kg every 8 h, or vancomycin, 17.5 mg/kg every 6 h, for 4 days. Both antimicrobial agent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaatz, G W, Seo, S M, Barriere, S L, Albrecht, L M, Rybak, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC245216/
https://ncbi.nlm.nih.gov/pubmed/1929325
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