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Development of resistance to fleroxacin during therapy of experimental methicillin-susceptible Staphylococcus aureus endocarditis.

The efficacy of fleroxacin was compared with that of vancomycin by using the rabbit model of methicillin-susceptible Staphylococcus aureus endocarditis. Animals received intravenous therapy with fleroxacin, 30 mg/kg every 8 h, or vancomycin, 17.5 mg/kg every 6 h, for 4 days. Both antimicrobial agent...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Kaatz, G W, Seo, S M, Barriere, S L, Albrecht, L M, Rybak, M J
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 1991
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245216/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.8.1547
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