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Pharmacokinetics of cefotaxime and desacetylcefotaxime in patients with liver disease.

The dispositions of cefotaxime and its metabolite desacetylcefotaxime were investigated in patients with different forms of chronic parenchymal liver disease (CPLD). A total of 31 subjects (27 patients and 4 controls) received a single 2-g dose of cefotaxime by infusion, and serial blood samples wer...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Ko, R J, Sattler, F R, Nichols, S, Akriviadis, E, Runyon, B, Appleman, M, Cohen, J L, Koda, R T
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1376
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