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Pharmacokinetics of cefotaxime and desacetylcefotaxime in patients with liver disease.

The dispositions of cefotaxime and its metabolite desacetylcefotaxime were investigated in patients with different forms of chronic parenchymal liver disease (CPLD). A total of 31 subjects (27 patients and 4 controls) received a single 2-g dose of cefotaxime by infusion, and serial blood samples wer...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Ko, R J, Sattler, F R, Nichols, S, Akriviadis, E, Runyon, B, Appleman, M, Cohen, J L, Koda, R T
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1376
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