Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs.

Pneumocystis carinii was obtained in high yield from the lungs of immunosuppressed rats by rupturing mammalian host cells, washing away the soluble mammalian dihydrofolate reductase, and harvesting intact organisms in association with the mammalian plasma membranes. P. carinii dihydrofolate reductas...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Broughton, M C, Queener, S F
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245170/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1348
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