Antifungal effects of the nonlinear pharmacokinetics of cilofungin, a 1,3-beta-glucan synthetase inhibitor, during continuous and intermittent intravenous infusions in treatment of experimental disseminated candidiasis.

Cilofungin (LY-121019) is a fungicidal cell wall-active 1,3-beta-glucan synthetase inhibitor with a short plasma half-life and saturable nonlinear plasma pharmacokinetics. To optimize the in vivo efficacy of this compound, we studied the effects of its linear and nonlinear pharmacokinetics during co...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Walsh, T J, Lee, J W, Kelly, P, Bacher, J, Lecciones, J, Thomas, V, Lyman, C, Coleman, D, Gordee, R, Pizzo, P A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC245165/
https://ncbi.nlm.nih.gov/pubmed/1929288
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker