Limited protection by small unilamellar liposomes against the renal tubular toxicity induced by repeated amphotericin B infusions in rats.

Amphotericin B (AMB), either alone or incorporated into small unilamellar vesicles of pure dipalmitoylphosphatidyl choline (DPPC SUV-AMB), was administered intravenously to male Sprague-Dawley rats once daily for 5 days. Either 1.5 or 3.5 mg of AMB or DPPC SUV-AMB per kg was given, since these conce...

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Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Longuet, P, Joly, V, Amirault, P, Seta, N, Carbon, C, Yeni, P
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245162/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1303
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