Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.

We used a viral endpoint dilution assay to show changes in the proportion of zidovudine (azidothymidine; AZT)-resistant viruses within a heterogeneous mixture of human immunodeficiency virus type 1 (HIV-1) quasispecies isolated from patients on long-term AZT therapy. Several HIV-1 isolates, which co...

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Detalhes bibliográficos
Main Authors: Rooke, R, Parniak, M A, Tremblay, M, Soudeyns, H, Li, X G, Gao, Q, Yao, X J, Wainberg, M A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC245142/
https://ncbi.nlm.nih.gov/pubmed/1649576
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