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Susceptibilities of zidovudine-resistant variants of human immunodeficiency virus type 1 to inhibition by acyclic nucleoside phosphonates.

The acyclic purine nucleoside phosphonates, a newly described class of broad-spectrum antiviral agents, effectively inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro and in animal AIDS models. 9-(2-Phosphonylmethoxyethyl)adenine (PMEA) is currently being evaluated in clinical...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Gong, Y F, Marshall, D R, Srinivas, R V, Fridland, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7979311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.7.1683
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