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Effect of monodesethyl amodiaquine on human polymorphonuclear neutrophil functions in vitro.

We have previously observed that the antimalarial drug amodiaquine impairs the human polymorphonuclear neutrophil (PMN) oxidative burst in vitro. However, the drug acted at a concentration of 100 micrograms/ml, far higher than that which is achievable therapeutically. Since amodiaquine is extensivel...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Labro, M T, el Benna, J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.824
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