Urocortin ameliorates diabetic nephropathy in obese db/db mice

BACKGROUND AND PURPOSE: Hyperglycaemia induces overproduction of mitochondrial reactive oxygen species (ROS) in endothelial cells, which is believed to be a major molecular mechanism underlying complications of diabetes, including diabetic nephropathy. Impairment of endothelium-dependent vasodilatat...

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Main Authors: Li, X, Hu, J, Zhang, R, Sun, X, Zhang, Q, Guan, X, Chen, J, Zhu, Q, Li, S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2451047/
https://ncbi.nlm.nih.gov/pubmed/18587447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.155
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