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Pharmacokinetics of the penem CP-65,207 and its separate stereoisomers in humans.

CP-65,207 is a new broad-spectrum penem antimicrobial agent that is a 1:1 mixture of two stereoisomers. Five minutes after a 10-min intravenous infusion of 1 g of CP-65,207 to volunteers, mean concentrations in serum were 33 micrograms of the R isomer per ml and 29 micrograms of the S isomer per ml....

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Foulds, G, Knirsch, A K, Lazar, J D, Tensfelt, T G, Gerber, N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2069372/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.4.665
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