Pharmacokinetics of the penem CP-65,207 and its separate stereoisomers in humans.

CP-65,207 is a new broad-spectrum penem antimicrobial agent that is a 1:1 mixture of two stereoisomers. Five minutes after a 10-min intravenous infusion of 1 g of CP-65,207 to volunteers, mean concentrations in serum were 33 micrograms of the R isomer per ml and 29 micrograms of the S isomer per ml....

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Foulds, G, Knirsch, A K, Lazar, J D, Tensfelt, T G, Gerber, N
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245076/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2069372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.4.665
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