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Effectiveness of clarithromycin and minocycline alone and in combination against experimental Mycobacterium leprae infection in mice.

As determined by the proportional bactericide method, clarithromycin had strong bactericidal activity against Mycobacterium leprae. Clarithromycin was administered to mice by gavage as 20 daily doses at dosages of 12.5 to 50 mg/kg of body weight. At a dosage of 25 mg/kg, minocycline was more active...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Ji, B, Perani, E G, Grosset, J H
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1828136/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.579
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