Effectiveness of clarithromycin and minocycline alone and in combination against experimental Mycobacterium leprae infection in mice.
As determined by the proportional bactericide method, clarithromycin had strong bactericidal activity against Mycobacterium leprae. Clarithromycin was administered to mice by gavage as 20 daily doses at dosages of 12.5 to 50 mg/kg of body weight. At a dosage of 25 mg/kg, minocycline was more active...
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| Publicado en: | Antimicrob Agents Chemother |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1991
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1828136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.579 |
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