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SDZ MRL 953, a novel immunostimulatory monosaccharidic lipid A analog with an improved therapeutic window in experimental sepsis.

SDZ MRL 953, a new synthetic monosaccharidic lipid A, was investigated in vitro and in vivo for immunopharmacological activities. In experimental models of microbial infections, the compound was highly protective when it was administered prophylactically either once or three times to myelosuppressed...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Lam, C, Schütze, E, Hildebrandt, J, Aschauer, H, Liehl, E, Macher, I, Stütz, P
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2039200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.500
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