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SDZ MRL 953, a novel immunostimulatory monosaccharidic lipid A analog with an improved therapeutic window in experimental sepsis.

SDZ MRL 953, a new synthetic monosaccharidic lipid A, was investigated in vitro and in vivo for immunopharmacological activities. In experimental models of microbial infections, the compound was highly protective when it was administered prophylactically either once or three times to myelosuppressed...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Lam, C, Schütze, E, Hildebrandt, J, Aschauer, H, Liehl, E, Macher, I, Stütz, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2039200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.500
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