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Preferential hydrolysis of cis configuration compounds at the 3,4 position of monobactams by beta-lactamase from Morganella morganii.

Carumonam and BO-1166 (cis configuration) were inactivated by beta-lactamase of Morganella morganii more rapidly than were aztreonam and BO-1165 (trans configuration), as demonstrated by spectrophotometric analysis and microbiological assay. An active enzyme was recovered more rapidly from the inact...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Matsuda, K, Sanada, M, Nakagawa, S, Inoue, M, Mitsuhashi, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245032/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2039196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.458
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