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Preferential hydrolysis of cis configuration compounds at the 3,4 position of monobactams by beta-lactamase from Morganella morganii.

Carumonam and BO-1166 (cis configuration) were inactivated by beta-lactamase of Morganella morganii more rapidly than were aztreonam and BO-1165 (trans configuration), as demonstrated by spectrophotometric analysis and microbiological assay. An active enzyme was recovered more rapidly from the inact...

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Detalles Bibliográficos
Main Authors: Matsuda, K, Sanada, M, Nakagawa, S, Inoue, M, Mitsuhashi, S
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC245032/
https://ncbi.nlm.nih.gov/pubmed/2039196
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