Mechanism of action of anticandidal dipeptides containing inhibitors of glucosamine-6-phosphate synthase.

The mechanism of anticandidal action of novel synthetic dipeptides containing N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP) residues was shown to be consistent with the "warhead delivery" concept. FMDP dipeptides were shown to be transported into Candida albicans cells by the d...

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Bibliographic Details
Main Authors: Milewski, S, Andruszkiewicz, R, Kasprzak, L, Mazerski, J, Mignini, F, Borowski, E
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC244938/
https://ncbi.nlm.nih.gov/pubmed/1901701
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