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Mechanism of action of anticandidal dipeptides containing inhibitors of glucosamine-6-phosphate synthase.

The mechanism of anticandidal action of novel synthetic dipeptides containing N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP) residues was shown to be consistent with the "warhead delivery" concept. FMDP dipeptides were shown to be transported into Candida albicans cells by the d...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Milewski, S, Andruszkiewicz, R, Kasprzak, L, Mazerski, J, Mignini, F, Borowski, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901701/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.1.36
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