Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy

Strategies to treat cancer have focused primarily on the killing of tumor cells. Here, we describe a differential stress resistance (DSR) method that focuses instead on protecting the organism but not cancer cells against chemotherapy. Short-term starved S. cerevisiae or cells lacking proto-oncogene...

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Bibliografiske detaljer
Main Authors: Raffaghello, Lizzia, Lee, Changhan, Safdie, Fernando M., Wei, Min, Madia, Federica, Bianchi, Giovanna, Longo, Valter D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Reactive Oxygen Species Special Feature
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448817/
https://ncbi.nlm.nih.gov/pubmed/18378900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708100105
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