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Starvation, detoxification, and multidrug resistance in cancer therapy

The selection of chemotherapy drugs is based on the cytotoxicity to specific tumor cell types and the relatively low toxicity to normal cells and tissues. However, the toxicity to normal cells poses a major clinical challenge, particularly when malignant cells have acquired resistance to chemotherap...

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Detalhes bibliográficos
Main Authors: Lee, Changhan, Raffaghello, Lizzia, Longo, Valter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573885/
https://ncbi.nlm.nih.gov/pubmed/22391012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2012.01.004
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