Quantifying changes in the thiol redox proteome upon oxidative stress in vivo

Antimicrobial levels of reactive oxygen species (ROS) are produced by the mammalian host defense to kill invading bacteria and limit bacterial colonization. One main in vivo target of ROS is the thiol group of proteins. We have developed a quantitative thiol trapping technique termed OxICAT to ident...

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Hauptverfasser: Leichert, Lars I., Gehrke, Florian, Gudiseva, Harini V., Blackwell, Tom, Ilbert, Marianne, Walker, Angela K., Strahler, John R., Andrews, Philip C., Jakob, Ursula
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Reactive Oxygen Species Special Feature
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448814/
https://ncbi.nlm.nih.gov/pubmed/18287020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707723105
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