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Quantifying changes in the thiol redox proteome upon oxidative stress in vivo

Antimicrobial levels of reactive oxygen species (ROS) are produced by the mammalian host defense to kill invading bacteria and limit bacterial colonization. One main in vivo target of ROS is the thiol group of proteins. We have developed a quantitative thiol trapping technique termed OxICAT to ident...

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Detalhes bibliográficos
Main Authors: Leichert, Lars I., Gehrke, Florian, Gudiseva, Harini V., Blackwell, Tom, Ilbert, Marianne, Walker, Angela K., Strahler, John R., Andrews, Philip C., Jakob, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448814/
https://ncbi.nlm.nih.gov/pubmed/18287020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707723105
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