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Torpor in mice is induced by both leptin-dependent and -independent mechanisms

We tested the effect of chronic leptin treatment on fasting-induced torpor in leptin-deficient A-ZIP/F-1 and ob/ob mice. A-ZIP/F-1 mice have virtually no white adipose tissue and low leptin levels, whereas ob/ob mice have an abundance of fat but no leptin. These two models allowed us to examine the...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gavrilova, Oksana, Leon, Lisa R., Marcus-Samuels, Bernice, Mason, Mark M., Castle, Arthur L., Refetoff, Samuel, Vinson, Charles, Reitman, Marc L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10588755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.25.14623
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