Androgen receptor–negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms

In prostate cancer, androgen blockade strategies are commonly used to treat osteoblastic bone metastases. However, responses to these therapies are typically brief, and the mechanism underlying androgen-independent progression is not clear. Here, we established what we believe to be the first human...

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Detalhes bibliográficos
Main Authors: Li, Zhi Gang, Mathew, Paul, Yang, Jun, Starbuck, Michael W., Zurita, Amado J., Liu, Jie, Sikes, Charles, Multani, Asha S., Efstathiou, Eleni, Lopez, Adriana, Wang, Jing, Fanning, Tina V., Prieto, Victor G., Kundra, Vikas, Vazquez, Elba S., Troncoso, Patricia, Raymond, Austin K., Logothetis, Christopher J., Lin, Sue-Hwa, Maity, Sankar, Navone, Nora M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447924/
https://ncbi.nlm.nih.gov/pubmed/18618013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33093
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