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Altered Metabolism of Growth Hormone Receptor Mutant Mice: A Combined NMR Metabonomics and Microarray Study

BACKGROUND: Growth hormone is an important regulator of post-natal growth and metabolism. We have investigated the metabolic consequences of altered growth hormone signalling in mutant mice that have truncations at position 569 and 391 of the intracellular domain of the growth hormone receptor, and...

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主要な著者: Schirra, Horst Joachim, Anderson, Cameron G., Wilson, William J., Kerr, Linda, Craik, David J., Waters, Michael J., Lichanska, Agnieszka M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447874/
https://ncbi.nlm.nih.gov/pubmed/18648510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002764
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