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Altered Metabolism of Growth Hormone Receptor Mutant Mice: A Combined NMR Metabonomics and Microarray Study

BACKGROUND: Growth hormone is an important regulator of post-natal growth and metabolism. We have investigated the metabolic consequences of altered growth hormone signalling in mutant mice that have truncations at position 569 and 391 of the intracellular domain of the growth hormone receptor, and...

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Detalhes bibliográficos
Main Authors: Schirra, Horst Joachim, Anderson, Cameron G., Wilson, William J., Kerr, Linda, Craik, David J., Waters, Michael J., Lichanska, Agnieszka M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447874/
https://ncbi.nlm.nih.gov/pubmed/18648510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002764
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