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TNF-α Antagonism Generates a Population of Antigen-Specific CD4(+)CD25(+) T Cells That Inhibit Protective Immunity in Murine Histoplasmosis
In both humans and mice, treatment with TNF-α antagonists is associated with serious infectious complications including disseminated histoplasmosis. The mechanisms by which inhibition of endogenous TNF-α alter protective immunity remain obscure. Herein, we tested the possibility that neutralization...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447823/ https://ncbi.nlm.nih.gov/pubmed/18178849 |
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