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T Cells Require Tumor Necrosis Factor-α to Provide Protective Immunity in Mice Infected with Histoplasma capsulatum

We examined whether neutralization of tumor necrosis factor (TNF)-α after intranasal exposure of mice to Histoplasma capsulatum was necessary for control of primary or secondary infection. All mice given monoclonal antibody to TNF-α on the day of infection or on day 3 after infection died. When anti...

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Bibliographic Details
Main Authors: Deepe, George S., Gibbons, Reta S.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1390767/
https://ncbi.nlm.nih.gov/pubmed/16362898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/498981
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