Enamel Defects and Ameloblast-specific Expression in Enam Knock-out/lacZ Knock-in Mice

Enamelin is critical for proper dental enamel formation, and defects in the human enamelin gene cause autosomal dominant amelogenesis imperfecta. We used gene targeting to generate a knock-in mouse carrying a null allele of enamelin (Enam) that has a lacZ reporter gene replacing the Enam translation...

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Autors principals: Hu, Jan C.-C., Hu, Yuanyuan, Smith, Charles E., McKee, Marc D., Wright, J. Timothy, Yamakoshi, Yasuo, Papagerakis, Petros, Hunter, Graeme K., Feng, Jerry Q., Yamakoshi, Fumiko, Simmer, James P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447669/
https://ncbi.nlm.nih.gov/pubmed/18252720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710565200
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