Decreasing Intracellular Superoxide Corrects Defective Ischemia-induced New Vessel Formation in Diabetic Mice

Tissue ischemia promotes vasculogenesis through chemokine-induced recruitment of bone marrow-derived endothelial progenitor cells (EPCs). Diabetes significantly impairs this process. Because hyperglycemia increases reactive oxygen species in a number of cell types, and because many of the defects re...

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Detalhes bibliográficos
Main Authors: Ceradini, Daniel J., Yao, Dachun, Grogan, Raymon H., Callaghan, Matthew J., Edelstein, Diane, Brownlee, Michael, Gurtner, Geoffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447622/
https://ncbi.nlm.nih.gov/pubmed/18227068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707451200
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