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Mutations in the Amino Terminus of Foamy Virus Gag Disrupt Morphology and Infectivity but Do Not Target Assembly

Foamy viruses (FVs) assemble using pathways distinct from those of orthoretroviruses. FV capsid assembly takes place near the host microtubule-organizing center (MTOC). Assembled capsids then migrate by an unknown mechanism to the trans-Golgi network to colocalize with the FV glycoprotein, Env. Inte...

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Detalhes bibliográficos
Main Authors: Life, Rachel B., Lee, Eun-Gyung, Eastman, Scott W., Linial, Maxine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447090/
https://ncbi.nlm.nih.gov/pubmed/18434404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00503-08
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