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Impact of Individual Mutations on Increased Fitness in Adaptively Evolved Strains of Escherichia coli

We measured the relative fitness among a set of experimentally evolved Escherichia coli strains differing by a small number of adaptive mutations by directly measuring allelic frequencies in head-to-head competitions using a mass spectrometry-based method. We compared the relative effects of mutatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Applebee, M. Kenyon, Herrgård, Markus J., Palsson, Bernhard Ø.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447027/
https://ncbi.nlm.nih.gov/pubmed/18487343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01976-07
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