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R5X4 Viruses Are Evolutionary, Functional, and Antigenic Intermediates in the Pathway of a Simian-Human Immunodeficiency Virus Coreceptor Switch

To examine the pathway of the coreceptor switching of CCR5-using (R5) virus to CXCR4-using (X4) virus in simian-human immunodeficiency virus SHIV(SF162P3N)-infected rhesus macaque BR24, analysis was performed on variants present at 20 weeks postinfection, the time when the signature gp120 V3 loop se...

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Bibliografiske detaljer
Main Authors: Tasca, Silvana, Ho, Siu-Hong, Cheng-Mayer, Cecilia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446975/
https://ncbi.nlm.nih.gov/pubmed/18480460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00570-08
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