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VirB3 to VirB6 and VirB8 to VirB11, but Not VirB7, Are Essential for Mediating Persistence of Brucella in the Reticuloendothelial System

The Brucella abortus virB locus contains 12 open reading frames, termed virB1 through virB12, which encode a type IV secretion system. Polar mutations in the virB locus markedly reduce the ability of B. abortus to survive in cultured macrophages or to persist in organs of mice. While a nonpolar dele...

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Main Authors: den Hartigh, Andreas B., Rolán, Hortensia G., de Jong, Maarten F., Tsolis, Renée M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446811/
https://ncbi.nlm.nih.gov/pubmed/18469100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00406-08
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