Incorporation of Mycobacterium tuberculosis Lipoarabinomannan into Macrophage Membrane Rafts Is a Prerequisite for the Phagosomal Maturation Block

Lipoarabinomannan (LAM) is one of the key virulence factors for Mycobacterium tuberculosis, the etiological agent of tuberculosis. During uptake of mycobacteria, LAM interacts with the cell membrane of the host macrophage and can be detected throughout the cell upon infection. LAM can inhibit phagos...

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Bibliographic Details
Main Authors: Welin, Amanda, Winberg, Martin E., Abdalla, Hana, Särndahl, Eva, Rasmusson, Birgitta, Stendahl, Olle, Lerm, Maria
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446741/
https://ncbi.nlm.nih.gov/pubmed/18426888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01549-07
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