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Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis

Mycobacterium tuberculosis (Mtb) infects lung macrophages, which instead of killing the pathogen can be manipulated by the bacilli, creating an environment suitable for intracellular replication and spread to adjacent cells. The role of host cell death during Mtb infection is debated because the bac...

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Hlavní autoři: Welin, Amanda, Eklund, Daniel, Stendahl, Olle, Lerm, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102687/
https://ncbi.nlm.nih.gov/pubmed/21637850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020302
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