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Inactivation of the Type IV Secretion System Reduces the Th1 Polarization of the Immune Response to Brucella abortus Infection

The Brucella abortus type IV secretion system (T4SS), encoded by the virB operon, is essential for establishing persistent infection in the murine reticuloendothelial system. To gain insight into the in vivo interactions mediated by the T4SS, we compared host responses elicited by B. abortus with th...

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Autori principali: Rolán, Hortensia García, Tsolis, Renée M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446720/
https://ncbi.nlm.nih.gov/pubmed/18458071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00203-08
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