A Cyanobacterial Lipopolysaccharide Antagonist Inhibits Cytokine Production Induced by Neisseria meningitidis in a Human Whole-Blood Model of Septicemia

Septicemia caused by Neisseria meningitidis is characterized by increasing levels of meningococcal lipopolysaccharide (Nm-LPS) and cytokine production in the blood. We have used an in vitro human whole-blood model of meningococcal septicemia to investigate the potential of CyP, a selective Toll-like...

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Main Authors: Jemmett, Kim, Macagno, Annalisa, Molteni, Monica, Heckels, John E., Rossetti, Carlo, Christodoulides, Myron
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446719/
https://ncbi.nlm.nih.gov/pubmed/18443097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00110-08
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