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Increased Respiration in the sch9Δ Mutant Is Required for Increasing Chronological Life Span but Not Replicative Life Span

Loss of the protein kinase Sch9p increases both the chronological life span (CLS) and the replicative life span (RLS) of Saccharomyces cerevisiae by mimicking calorie restriction, but the physiological consequences of SCH9 deletion are poorly understood. By transcriptional profiling of an sch9Δ muta...

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Detalhes bibliográficos
Main Authors: Lavoie, Hugo, Whiteway, Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446671/
https://ncbi.nlm.nih.gov/pubmed/18469137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00330-07
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