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Increased Respiration in the sch9Δ Mutant Is Required for Increasing Chronological Life Span but Not Replicative Life Span

Loss of the protein kinase Sch9p increases both the chronological life span (CLS) and the replicative life span (RLS) of Saccharomyces cerevisiae by mimicking calorie restriction, but the physiological consequences of SCH9 deletion are poorly understood. By transcriptional profiling of an sch9Δ muta...

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Bibliografiske detaljer
Main Authors: Lavoie, Hugo, Whiteway, Malcolm
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446671/
https://ncbi.nlm.nih.gov/pubmed/18469137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00330-07
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