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Dendritic Cells Differentiated in the Presence of a Single-Stranded Viral RNA Sequence Conserve Their Ability To Activate CD4 T Lymphocytes but Lose Their Capacity for Th1 Polarization

Monocyte-derived dendritic cells (DCs) differentiate in the presence of Toll-like-receptor (TLR) ligands in the course of ongoing infections. A single-stranded RNA (ssRNA) sequence, corresponding to the sequence of the U5 region of human immunodeficiency virus type 1 RNA, was used to mimic viral act...

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Detalhes bibliográficos
Main Authors: Marin-Esteban, Viviana, Abdul, Mubashira, Charron, Dominique, Haziot, Alain, Mooney, Nuala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446623/
https://ncbi.nlm.nih.gov/pubmed/18400975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00428-07
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