Monocyte-Derived Dendritic Cells Differentiated in the Presence of Lenalidomide Display a Semi-Mature Phenotype, Enhanced Phagocytic Capacity, and Th1 Polarization Capability

Lenalidomide is an analog of thalidomide, with potent anticancer activity demonstrated in several hematological malignancies. It has immunomodulatory properties, being able to enhance the activation of different types of immune cells, which results in antitumor activities. Dendritic cells (DCs) are...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: López-Relaño, Juan, Martín-Adrados, Beatriz, Real-Arévalo, Irene, Lozano-Bartolomé, Javier, Abós, Beatriz, Sánchez-Ramón, Silvia, Alonso, Bárbara, Gómez del Moral, Manuel, Martínez-Naves, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008535/
https://ncbi.nlm.nih.gov/pubmed/29951065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01328
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